Antibacterial Potential of Biosynthesised Silver Nanoparticles from Serratia sp. AQ5-NT39 against Aeromonas hydrophila.

Abstract

While the public health community is concerned about the notable rise in Aeromonas hydrophila resistance to specific antibiotics, a consistent and rigorous approach is needed to manage this opportunistic pathogen’s global presence in the aquaculture sector. It has been demonstrated that Serratia sp. strain AQ5- NT39 can biosynthesise silver nanoparticles (AgNPs) through extracellular biosynthesis and exhibit antibacterial activity against pathogenic bacteria. This study will investigate in vitro the interaction of biosynthesised AgNPs by Serratia sp. strain AQ5- NT39 against A. hydrophila using Kirby-Bauer disk diffusion, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). AgNPs AQ5-NT39 demonstrated by forming inhibition zones in the disk diffusion at 8 mm, which showed strong antibacterial activity against A. hydrophila. Additionally, the MIC and MBC values at 8 ppm determined the inhibitory and bactericidal effects of the AgNPs. These results underscore the importance of exploring novel nanoparticle applications and their potential antimicrobial implications for addressing bacterial infections in aquatic environments.